diff --git a/Library/Homebrew/cleanup.rb b/Library/Homebrew/cleanup.rb
index 3e4e624dc2..45e3b35ddc 100644
--- a/Library/Homebrew/cleanup.rb
+++ b/Library/Homebrew/cleanup.rb
@@ -36,7 +36,7 @@ module CleanupRefinement
     end
 
     def nested_cache?
-      directory? && %w[go_cache glide_home java_cache npm_cache gclient_cache].include?(basename.to_s)
+      directory? && %w[cargo_cache go_cache glide_home java_cache npm_cache gclient_cache].include?(basename.to_s)
     end
 
     def go_cache_directory?
diff --git a/Library/Homebrew/formula.rb b/Library/Homebrew/formula.rb
index af2c449d7e..e1e5262fe0 100644
--- a/Library/Homebrew/formula.rb
+++ b/Library/Homebrew/formula.rb
@@ -1680,6 +1680,7 @@ class Formula
       HOMEBREW_PATH: nil,
       _JAVA_OPTIONS: "#{ENV["_JAVA_OPTIONS"]} -Duser.home=#{HOMEBREW_CACHE}/java_cache",
       GOCACHE: "#{HOMEBREW_CACHE}/go_cache",
+      CARGO_HOME: "#{HOMEBREW_CACHE}/cargo_cache",
     }
 
     ENV.clear_sensitive_environment!
@@ -2034,6 +2035,7 @@ class Formula
         stage_env[:_JAVA_OPTIONS] =
           "#{ENV["_JAVA_OPTIONS"]} -Duser.home=#{HOMEBREW_CACHE}/java_cache"
         stage_env[:GOCACHE] = "#{HOMEBREW_CACHE}/go_cache"
+        stage_env[:CARGO_HOME] = "#{HOMEBREW_CACHE}/cargo_cache"
         stage_env[:CURL_HOME] = ENV["CURL_HOME"] || ENV["HOME"]
       end
 
diff --git a/Library/Homebrew/test/cleanup_spec.rb b/Library/Homebrew/test/cleanup_spec.rb
index 6df872f20d..3ec556fdeb 100644
--- a/Library/Homebrew/test/cleanup_spec.rb
+++ b/Library/Homebrew/test/cleanup_spec.rb
@@ -225,6 +225,15 @@ describe Homebrew::Cleanup do
       expect(incomplete).not_to exist
     end
 
+    it "cleans up 'cargo_cache'" do
+      cargo_cache = (HOMEBREW_CACHE/"cargo_cache")
+      cargo_cache.mkpath
+
+      subject.cleanup_cache
+
+      expect(cargo_cache).not_to exist
+    end
+
     it "cleans up 'go_cache'" do
       go_cache = (HOMEBREW_CACHE/"go_cache")
       go_cache.mkpath