diff --git a/Library/Homebrew/dev-cmd/install-bundler-gems.rb b/Library/Homebrew/dev-cmd/install-bundler-gems.rb
index 7d5377da05..742ed9ef6d 100644
--- a/Library/Homebrew/dev-cmd/install-bundler-gems.rb
+++ b/Library/Homebrew/dev-cmd/install-bundler-gems.rb
@@ -30,7 +30,7 @@ module Homebrew
     Homebrew::Settings.delete(:gemgroups) if groups
 
     groups ||= []
-    groups |= VALID_GEM_GROUPS if groups.delete("all")
+    groups |= Homebrew.valid_gem_groups if groups.delete("all")
 
     Homebrew.install_bundler_gems!(groups: groups)
   end
diff --git a/Library/Homebrew/dev-cmd/typecheck.rb b/Library/Homebrew/dev-cmd/typecheck.rb
index 47ee39c1f3..37805c83ba 100644
--- a/Library/Homebrew/dev-cmd/typecheck.rb
+++ b/Library/Homebrew/dev-cmd/typecheck.rb
@@ -46,7 +46,7 @@ module Homebrew
     args = typecheck_args.parse
 
     update = args.update? || args.update_all?
-    groups = update ? VALID_GEM_GROUPS : ["sorbet"]
+    groups = update ? Homebrew.valid_gem_groups : ["sorbet"]
     Homebrew.install_bundler_gems!(groups: groups)
 
     HOMEBREW_LIBRARY_PATH.cd do
diff --git a/Library/Homebrew/dev-cmd/vendor-gems.rb b/Library/Homebrew/dev-cmd/vendor-gems.rb
index c284e17764..30ddc13b27 100644
--- a/Library/Homebrew/dev-cmd/vendor-gems.rb
+++ b/Library/Homebrew/dev-cmd/vendor-gems.rb
@@ -30,7 +30,7 @@ module Homebrew
 
     Homebrew.install_bundler!
 
-    ENV["BUNDLE_WITH"] = VALID_GEM_GROUPS.join(":")
+    ENV["BUNDLE_WITH"] = Homebrew.valid_gem_groups.join(":")
 
     # System Ruby does not pick up the correct SDK by default.
     ENV["SDKROOT"] = MacOS.sdk_path if ENV["HOMEBREW_MACOS_SYSTEM_RUBY_NEW_ENOUGH"]
diff --git a/Library/Homebrew/utils/gems.rb b/Library/Homebrew/utils/gems.rb
index 626b9f0408..1a15f9e29d 100644
--- a/Library/Homebrew/utils/gems.rb
+++ b/Library/Homebrew/utils/gems.rb
@@ -12,10 +12,26 @@ module Homebrew
   # After updating this, run `brew vendor-gems --update=--bundler`.
   HOMEBREW_BUNDLER_VERSION = "2.3.26"
 
-  VALID_GEM_GROUPS = ["sorbet", "prof"].freeze
-
   module_function
 
+  # @api private
+  def gemfile
+    File.join(ENV.fetch("HOMEBREW_LIBRARY"), "Homebrew", "Gemfile")
+  end
+
+  # @api private
+  def valid_gem_groups
+    install_bundler!
+    require "bundler"
+
+    Bundler.with_unbundled_env do
+      ENV["BUNDLE_GEMFILE"] = gemfile
+      groups = Bundler::Definition.build(Bundler.default_gemfile, Bundler.default_lockfile, false).groups
+      groups.delete(:default)
+      groups.map(&:to_s)
+    end
+  end
+
   def ruby_bindir
     "#{RbConfig::CONFIG["prefix"]}/bin"
   end
@@ -136,7 +152,7 @@ module Homebrew
     old_bundle_frozen = ENV.fetch("BUNDLE_FROZEN", nil)
     old_sdkroot = ENV.fetch("SDKROOT", nil)
 
-    invalid_groups = groups - VALID_GEM_GROUPS
+    invalid_groups = groups - valid_gem_groups
     raise ArgumentError, "Invalid gem groups: #{invalid_groups.join(", ")}" unless invalid_groups.empty?
 
     install_bundler!
@@ -147,7 +163,7 @@ module Homebrew
     groups |= (Homebrew::Settings.read(:gemgroups)&.split(";") || [])
     groups.sort!
 
-    ENV["BUNDLE_GEMFILE"] = File.join(ENV.fetch("HOMEBREW_LIBRARY"), "Homebrew", "Gemfile")
+    ENV["BUNDLE_GEMFILE"] = gemfile
     ENV["BUNDLE_WITH"] = groups.join(" ")
     ENV["BUNDLE_FROZEN"] = "true"